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Pierre Abraham
- FACULTE DE SANTE
- 28 rue Roger Amsler - 49045 - ANGERS CEDEX 01
- Structure Fédérative de Recherche Interactions Cellulaires et Applications Thérapeutique : SFR ICAT
- 2 Rue Haute de Reculée - 49045 - ANGERS CEDEX 01
- Courriel : pierre.abraham @ univ-angers.fr
Afficher UFR de Médecine sur une carte plus grande
Discipline
Physiologie
Thèmes de recherche
Microcirculation, Exercise, Artériopathie oblitérante des membres inférieurs, Sport
CV
DIPLÔMES:
- Doctorat en Médecine : 1990
- D.E.S. de Cardiologie : 1990
- D.E.S.C. de Médecine Vasculaire : 1994
TITRES UNIVERSITAIRES:
- D.E.A. , Physiologie -1992
- Doctorat d'Université : Physiologie 1995
- Habilitation à diriger les recherches 1998
AUTRES DIPLOMES:
- Diplôme d'université d' Echocardiographie-Doppler : 1990
- Capacité de Médecine du Sport 1992.
- Diplôme d'université de Cardiologie du sport 1997
SERVICES DIVERS:
- Membre de la Commission TAPAM depuis septembre 2007
- Membre élu au conseil de gestion de l'UFR Médecine depuis 2012.
- Membre élu au conseil de SFR 4208 depuis 2012.
- Membre de la société française de Médecine du sport depuis 1997
- Membre de la société française de Médecine vasculaire depuis 2003
- Membre de la société Francaise de Cardiologie depuis 2003
- Membre de la société Française de Physiologie depuis 2005
- Président de la Société de Médecine du Sport de l'Ouest depuis mars 2010
- Membre du comité directeur de l'IFEPSA depuis 2006.
Publications
PUBLICATIONS RECENTES
1: Carsin-Mahé M, Abraham P, Le Faucheur A, Leftheriotis G, Mahé G. Simple routine assessment of dietary pattern in patients with peripheral artery disease. J Vasc Surg. 2012 Jul;56(1):281-2. PubMed PMID: 22749274.
2: Mahé G, Durand S, Humeau-Heurtier A, Leftheriotis G, Abraham P. Impact of experimental conditions on non-contact laser recordings in microvascular studies. Microcirculation. 2012 Jun 18. doi: 10.1111/j.1549-8719.2012.00205.x. [Epub ahead of print] PubMed PMID: 22708898.
3: Humeau-Heurtier A, Mahé G, Chapeau-Blondeau F, Rousseau D, Abraham P. Study of time reversibility/irreversibility of cardiovascular data: theoretical results and application to laser Doppler flowmetry and heart rate variability signals.Phys Med Biol. 2012 Jul 7;57(13):4335-51. Epub 2012 Jun 15. PubMed PMID: 22705853.
4: Bricq S, Mahé G, Rousseau D, Humeau-Heurtier A, Chapeau-Blondeau F, Rojas Varela J, Abraham P. Assessing spatial resolution versus sensitivity from laser speckle contrast imaging: application to frequency analysis. Med Biol Eng Comput. 2012 May 30. [Epub ahead of print] PubMed PMID: 22644256.
5: Abraham P, Ouedraogo N, Tew GA, Vielle B, Leftheriotis G, Mahe G. Aging reduces the accuracy of self-reported walking limitation in patients with vascular-type claudication. J Vasc Surg. 2012 May 24. [Epub ahead of print] PubMed PMID: 22633421.
6: Tew GA, Ouedraogo N, Nicolas G, Leftheriotis G, Copeland RJ, Abraham P. Impaired somatosensation in patients with isolated proximal-without-distal exercise-related lower-limb ischemia. Clin J Pain. 2012 Jun;28(5):404-9. PubMed PMID: 22395334.
7: Ouedraogo N, Marchand J, Bondarenko M, Picquet J, Leftheriotis G, Abraham P. Estimation of running capacity can likely be removed from questionnaires estimating walking impairment in patients with claudication. Eur J Vasc Endovasc Surg. 2012 Jun;43(6):705-10. Epub 2012 Mar 3. PubMed PMID: 22386592.
8: Abraham P, Noury-Desvaux B, Gernigon M, Mahé G, Sauvaget T, Leftheriotis G, Le Faucheur A. The inter- and intra-unit variability of a low-cost GPS data logger/receiver to study human outdoor walking in view of health and clinical studies. PLoS One. 2012;7(2):e31338. Epub 2012 Feb 20. PubMed PMID: 22363623; PubMed Central PMCID: PMC3282693.
9: Mahé G, Humeau-Heurtier A, Durand S, Leftheriotis G, Abraham P. Assessment of skin microvascular function and dysfunction with laser speckle contrast imaging. Circ Cardiovasc Imaging. 2012 Jan;5(1):155-63. Review. PubMed PMID: 22253335.
10: Abraham P, Tew GA, Abraham PS, Le Faucheur A. Brisk and prolonged daily walking is needed to outpace the Grim Reaper. BMJ. 2012 Jan 17;344:e424. doi: 10.1136/bmj.e424. PubMed PMID: 22252701.
11: Humeau-Heurtier A, Buard B, Mahe G, Abraham P. Laser speckle contrast imaging of the skin: interest in processing the perfusion data. Med Biol Eng Comput. 2012 Feb;50(2):103-5. Epub 2011 Dec 29. PubMed PMID: 22205575.
12: Piguel X, Abraham P, Bouhours-Nouet N, Gatelais F, Dufresne S, Rouleau S, Coutant R. Impaired aerobic exercise adaptation in children and adolescents with craniopharyngioma is associated with hypothalamic involvement. Eur J Endocrinol. 2012 Feb;166(2):215-22. Epub 2011 Nov 17. PubMed PMID: 22096113.
13: Mahé G, Durand S, Humeau A, Leftheriotis G, Rousseau P, Abraham P. Air movements interfere with laser speckle contrast imaging recordings. Lasers Med Sci. 2011 Nov 1. [Epub ahead of print] PubMed PMID: 22041847.
14: Mahe G, Ouedraogo N, Marchand J, Vielle B, Picquet J, Leftheriotis G, Abraham P. Self-reported estimation of usual walking speed improves the performance of questionnaires estimating walking capacity in patients with vascular-type claudication. J Vasc Surg. 2011 Nov;54(5):1360-5. PubMed PMID: 22027439.
15: Noury-Desvaux B, Abraham P, Mahé G, Sauvaget T, Leftheriotis G, Le Faucheur A. The accuracy of a simple, low-cost GPS data logger/receiver to study outdoor human walking in view of health and clinical studies. PLoS One. 2011;6(9):e23027. Epub 2011 Sep 13. PubMed PMID: 21931593; PubMed Central PMCID: PMC3172201.
16: Le Faucheur A, Noury-Desvaux B, Abraham P. Using global positioning system to assess walking capacity. Spine (Phila Pa 1976). 2011 Nov 15;36(24):2101; author reply 1201-2. PubMed PMID: 21912310.
17: Mahé G, Haj-Yassin F, Rousseau P, Humeau A, Durand S, Leftheriotis G, Abraham P. istance between laser head and skin does not influence skin blood flow values recorded by laser speckle imaging. Microvasc Res. 2011 Nov;82(3):439-42. Epub 2011 Jul 14. PubMed PMID: 21784084.
18: Lefthériotis G, Abraham P, Le Corre Y, Le Saux O, Henrion D, Ducluzeau PH, Prunier F, Martin L. Relationship between ankle brachial index and arterial remodeling in pseudoxanthoma elasticum. J Vasc Surg. 2011 Nov;54(5):1390-4. Epub 2011 Jul 1. PubMed PMID: 21723076.
19: Humeau A, Mahé G, Chapeau-Blondeau F, Rousseau D, Abraham P. Multiscale analysis of microvascular blood flow: a multiscale entropy study of laser Doppler flowmetry time series. IEEE Trans Biomed Eng. 2011 Oct;58(10):2970-3. Epub 2011 Jun 27. PubMed PMID: 21712149.
20: Sauvet F, Mahé G, Chennaoui M, Langrume C, Vasseur M, Abraham P, Leftheriotis G. Acetylcholine chloride as a potential source of variability in the study of cutaneous vascular function in man. Microvasc Res. 2011 Sep;82(2):190-7. Epub 2011 May 12. PubMed PMID: 21601579.
21: Maugin E, Abraham P, Paumier A, Mahé G, Enon B, Papon X, Picquet J. Patency of direct revascularisation of the hypogastric arteries in patients with aortoiliac occlusive disease. Eur J Vasc Endovasc Surg. 2011 Jul;42(1):78-82. Epub 2011 Apr 30. PubMed PMID: 21531593.
22: Lekakis J, Abraham P, Balbarini A, Blann A, Boulanger CM, Cockcroft J, Cosentino F, Deanfield J, Gallino A, Ikonomidis I, Kremastinos D, Landmesser U, Protogerou A, Stefanadis C, Tousoulis D, Vassalli G, Vink H, Werner N, Wilkinson I, Vlachopoulos C. Methods for evaluating endothelial function: a position statement from the European Society of Cardiology Working Group on Peripheral Circulation. Eur J Cardiovasc Prev Rehabil. 2011 Dec;18(6):775-89. Review. PubMed PMID: 21450600.
23: Rousseau P, Mahé G, Haj-Yassin F, Durand S, Humeau A, Leftheriotis G, Abraham P. Increasing the "region of interest" and "time of interest", both reduce the variability of blood flow measurements using laser speckle contrast imaging. Microvasc Res. 2011 Jul;82(1):88-91. Epub 2011 Mar 23. PubMed PMID: 21439303.
24: Ouedraogo N, Mahe G, Marchand J, Saïdi K, Leftheriotis G, Abraham P. Validation of a new simple questionnaire to "estimate ambulation capacity by history" (EACH) in patients with claudication. J Vasc Surg. 2011 Jul;54(1):133-8. pub 2011 Feb 18. PubMed PMID: 21334169.
25: Mahé G, Ouedraogo N, Leftheriotis G, Vielle B, Picquet J, Abraham P. Exercise treadmill testing in patients with claudication, with and without diabetes. Diabet Med. 2011 Mar;28(3):356-62. doi: 10.1111/j.1464-5491.2010.03208.x. PubMed PMID: 21309846.
26: Humeau A, Buard B, Mahé G, Rousseau D, Chapeau-Blondeau F, Abraham P. Multiscale entropy of laser Doppler flowmetry signals in healthy human subjects. Med Phys. 2010 Dec;37(12):6142-6. PubMed PMID: 21302770.
27: Ouedraogo N, Feuilloy M, Mahe G, Leftheriotis G, Saumet JL, Abraham P. Chest tcpO2 changes during constant-load treadmill walking tests in patients with claudication. Physiol Meas. 2011 Feb;32(2):181-94. Epub 2010 Dec 22. PubMed PMID: 21178246.
28: Mahé G, Rousseau P, Durand S, Bricq S, Leftheriotis G, Abraham P. Laser speckle contrast imaging accurately measures blood flow over moving skin surfaces. Microvasc Res. 2011 Mar;81(2):183-8. Epub 2010 Dec 13. PubMed PMID: 21156183.
29: Mahe G, Ouedraogo N, Vasseur M, Faligant C, Saidi K, Leftheriotis G, Abraham P. Limitations of self-reported estimates of functional capacity using the Walking Impairment Questionnaire. Eur J Vasc Endovasc Surg. 2011 Jan;41(1):104-9. Epub 2010 Nov 30. PubMed PMID: 21123095.
30: Humeau A, Buard B, Mahé G, Chapeau-Blondeau F, Rousseau D, Abraham P. Multifractal analysis of heart rate variability and laser Doppler flowmetry fluctuations:comparison of results from different numerical methods. Phys Med Biol. 2010 Oct 21;55(20):6279-97. Epub 2010 Oct 6. PubMed PMID: 20924134.
31: Mahé G, Zeenny M, Ouedraogo N, Vielle B, Leftheriotis G, Abraham P. Heart ate recovery after constant-load exercise tests is decreased in proportion to the importance (severity and diffusion) of exercise-induced lower-limb ischaemia. Clin Physiol Funct Imaging. 2011 Jan;31(1):48-53. doi: 0.1111/j.1475-097X.2010.00978.x. Epub 2010 Sep 17. PubMed PMID: 20849524.
32: Buard B, Mahé G, Chapeau-Blondeau F, Rousseau D, Abraham P, Humeau A. Generalized fractal dimensions of laser Doppler flowmetry signals recorded from glabrous and nonglabrous skin. Med Phys. 2010 Jun;37(6):2827-36. PubMed PMID: 20632594.
33: Abraham P, Ouedraogo N, Leftheriotis G. Diagnosing lumbar spinal stenosis. JAMA. 2010 Apr 21;303(15):1479-80; author reply 1480-1. PubMed PMID: 20407053.
34: Le Faucheur A, Noury-Desvaux B, Mahé G, Sauvaget T, Saumet JL, Leftheriotis G, Abraham P. Variability and short-term determinants of walking capacity in patients with intermittent claudication. J Vasc Surg. 2010 Apr;51(4):886-92. PubMed PMID: 20347684.
35: Mahe G, Abraham P, Zeenny M, Bruneau A, Vielle B, Leftheriotis G. Objective determination of the predefined duration of a constant-load diagnostic tests in arterial claudication. J Vasc Surg. 2010 Apr;51(4):863-8. PubMed PMID: 20347682.
36: Abraham P, Mahé G, Bruneau A, Leftheriotis G. Determinants of functional capacity in peripheral arterial disease. J Am Coll Cardiol. 2010 Feb 9;55(6):609-10; author reply 610-1. PubMed PMID: 20152568.
37: Biotteau E, Mahe G, Rousseau P, Leftheriotis G, Abraham P. Transcutaneous oxygen pressure measurements in diabetic and non-diabetic patients clinically suspected of severe limb ischemia: a matched paired retrospective analysis. Int Angiol. 2009 Dec;28(6):479-83. PubMed PMID: 20087286.
38: Paumier A, Abraham P, Mahé G, Maugin E, Enon B, Leftheriotis G, Picquet J. Functional outcome of hypogastric revascularisation for prevention of buttock claudication in patients with peripheral artery occlusive disease. Eur J Vasc Endovasc Surg. 2010 Mar;39(3):323-9. Epub 2009 Nov 11. PubMed PMID: 19910224.
39: Mahé G, Leftheriotis G, Picquet J, Jaquinandi V, Saumet JL, Abraham P. A normal penile pressure cannot rule out the presence of lesions on the arteries supplying the hypogastric circulation in patients with arterial claudication. Vasc Med. 2009 Nov;14(4):331-8. PubMed PMID: 19808718.
40: Fromy B, Sigaudo-Roussel D, Gaubert-Dahan ML, Rousseau P, Abraham P, Benzoni D, Berrut G, Saumet JL. Aging-associated sensory neuropathy alters pressure-induced vasodilation in humans. J Invest Dermatol. 2010 Mar;130(3):849-55. Epub 2009 Sep 3. PubMed PMID: 19727122.
41: Bruneau A, Le Faucheur A, Mahe G, Vielle B, Leftheriotis G, Abraham P. Endofibrosis in athletes: is a simple bedside exercise helpful or sufficient for the diagnosis? Clin J Sport Med. 2009 Jul;19(4):282-6. PubMed PMID: 19638821.
42: Rousseau P, Mahé G, Fromy B, Ducluzeau PH, Saumet JL, Abraham P. Axon-reflex cutaneous vasodilatation is impaired in type 2 diabetic patients receiving chronic low-dose aspirin. Microvasc Res. 2009 Sep;78(2):218-23. Epub 2009 Jun 23. PubMed PMID: 19555697.
43: Humeau A, Buard B, Chapeau-Blondeau F, Rousseau D, Mahe G, Abraham P. Multifractal analysis of central (electrocardiography) and peripheral (laser Doppler flowmetry) cardiovascular time series from healthy human subjects. Physiol Meas. 2009 Jul;30(7):617-29. Epub 2009 Jun 5. PubMed PMID: 19498219.
44: Mahe G, Rousseau P, Saumet JL, Abraham P. About "Chronic low-dose aspirin therapy attenuates reflex cutaneous vasodilatation in middle-aged humans". J Appl Physiol. 2009 Apr;106(4):1471; author reply 1472. PubMed PMID: 19336681.
45: Humeau A, Trzepizur W, Rousseau D, Chapeau-Blondeau F, Abraham P. Localization of transient signal high-values in laser Doppler flowmetry signals with an empirical mode decomposition. Med Phys. 2009 Jan;36(1):18-21. PubMed PMID: 19235369.
46: Jaquinandi V, Mahe G, Leftheriotis G, Saumet JL, Abraham P. Regarding "Reference value of transcutaneous oxygen measurement in diabetic patients compared with nondiabetic patients". J Vasc Surg. 2009 Jan;49(1):279-80; author reply 280-1. PubMed PMID: 19174273.
47: Trzepizur W, Gagnadoux F, Abraham P, Rousseau P, Meslier N, Saumet JL, Racineux JL. Microvascular endothelial function in obstructive sleep apnea: Impact of continuous positive airway pressure and mandibular advancement. Sleep Med. 2009 Aug;10(7):746-52. Epub 2009 Jan 14. PubMed PMID: 19147401.
48: Humeau A, Trzepizur W, Rousseau D, Chapeau-Blondeau F, Abraham P. Fisher information and Shannon entropy for on-line detection of transient signal high-values in laser Doppler flowmetry signals of healthy subjects. Phys Med Biol. 2008 Sep 21;53(18):5061-76. Epub 2008 Aug 22. PubMed PMID: 18723933.
49: Jaquinandi V, Saumet JL, Abraham P. Viewpoint: Fatigue mechanisms determining exercise performance: integrative physiology is systems physiology. J Appl Physiol. 2008 May;104(5):1545. PubMed PMID: 18504820.
50: Jaquinandi V, Picquet J, Saumet JL, Benharash P, Leftheriotis G, Abraham P. Functional assessment at the buttock level of the effect of aortobifemoral bypass surgery. Ann Surg. 2008 May;247(5):869-76. PubMed PMID: 18438126.
51: Humeau A, Chapeau-Blondeau F, Rousseau D, Rousseau P, Trzepizur W, Abraham P. Multifractality, sample entropy, and wavelet analyses for age-related changes in the peripheral cardiovascular system: preliminary results. Med Phys. 2008 Feb;35(2):717-23. PubMed PMID: 18383693.
52: Rousseau P, Tartas M, Fromy B, Godon A, Custaud MA, Saumet JL, Abraham P. Platelet inhibition by low-dose aspirin but not by clopidogrel reduces the axon-reflex current-induced vasodilation in humans. Am J Physiol Regul Integr Comp Physiol. 2008 May;294(5):R1420-6. Epub 2008 Feb 6. PubMed PMID: 18256140.
53: Le Faucheur A, Abraham P, Jaquinandi V, Bouyé P, Saumet JL, Noury-Desvaux B. Measurement of walking distance and speed in patients with peripheral arterial disease: a novel method using a global positioning system. Circulation. 2008 Feb 19;117(7):897-904. Epub 2008 Feb 4. PubMed PMID: 18250268.
54: Collette M, Humeau A, Abraham P. Time and spatial invariance of impedance signals in limbs of healthy subjects by time-frequency analysis. Ann Biomed Eng. 2008 Mar;36(3):444-51. Epub 2008 Jan 19. PubMed PMID: 18205048.
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